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BL4226   Chromatin and Genome Stability

Academic year(s): 2018-2019

Key information

SCOTCAT credits : 15

ECTS credits : 7

Level : SCQF level 10

Semester: 2

Availability restrictions: Not automatically available to General Degree students

Planned timetable: To be arranged

This module will introduce the fundamental concepts of chromatin structure and function and how this affects genome stability. DNA repair and telomere maintenance are perhaps the most significant factors affecting genome stability and these processes are central to the understanding of cancer cell biology. Indeed, most existing anti-cancer agents induce DNA damage and current efforts to target chromatin factors therapeutically are showing promise. You will have the opportunity to independently research and present seminars on the applied biology of chromatin and DNA repair within model organisms such as budding yeast, Caenorhabditis elegans and Drosophila melanogaster. Students will also have the opportunity to engage in research debates on topics at the forefront of modern cancer biology. Importantly, you will be expected to design and defend a research proposal that addresses an unsolved question of your choice within the field of genome stability.

Relationship to other modules

Pre-requisite(s): Before taking this module you must pass BL3302

Anti-requisite(s): You cannot take this module if you take BL5421

Learning and teaching methods and delivery

Weekly contact: 1 x 2-hour seminar (x 11 weeks)

Scheduled learning hours: 22

Guided independent study hours: 146

Assessment pattern

As used by St Andrews: 1.5-hour Written Examination = 20%, Coursework = 80%

As defined by QAA
Written examinations : 20%
Practical examinations : 0%
Coursework: 80%

Re-assessment: 1.5-hour Written Examination = 20%, Existing Coursework = 80%


Module coordinator: Dr H C Ferreira
Module teaching staff: Dr H Ferreira