BL4223
Eukaryotic chromosome replication and genome stability
2016-2017
15
7
SCQF level 10
1
Academic year(s): 2016-2017
SCOTCAT credits : 15
ECTS credits : 7
Level : SCQF level 10
Semester: 1
Planned timetable:
Highly-efficiently chromosomal DNA replication is essential for all forms of cellular life on Earth and requires the complex interplay of a large range of protein factors in a temporally- and spatially-coordinated manner. In humans, defects in the replication process may lead to genetic disease or cancer. This module will summarise current knowledge of the enzymes and mechanisms of chromosomal DNA replication in bacterial, archaeal and eukaryotic cells with particular emphasis on exploring the diverse range of experimental systems and techniques used in the laboratory to probe the structure, function and regulation of the replication apparatus. Similarities and differences between cellular and viral DNA replication strategies will be explored and diverse aspects of the evolution of the replication machinery highlighted.
Weekly contact:
Scheduled learning hours: 22
Guided independent study hours: 128
As used by St Andrews:
As defined by QAA
Written examinations : 60%
Practical examinations : 0%
Coursework: 40%