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CH4614   Heterocyclic and Pericyclic Chemistry

Academic year(s): 2019-2020

Key information

SCOTCAT credits : 10

ECTS credits : 5

Level : SCQF level 10

Semester: 1

Availability restrictions: Not automatically available to General Degree students

Planned timetable: To be arranged.

This module covers the important areas of heterocyclic and pericyclic chemistry in detail. In heterocyclic chemistry, the nomenclature and numbering of single and fused ring systems, and structure, reactivity, synthesis and applications of the main five and six-membered ring systems with one and two heteroatoms will be covered. Selected industrial syntheses of heterocyclic medicinal compounds are used to illustrate the basic principles as well as the factors to be considered in large scale synthesis. In pericyclic chemistry, a frontier molecular orbital approach based on the Woodward-Hoffmann rules will be applied to pericyclic reactions and used to provide an understanding of the energetics and stereochemistry of Diels-Alder and 1,3-dipolar cycloaddition reactions as well as electrocyclic processes and sigmatropic rearrangements. Synthetic applications of these processes will also be illustrated.

Relationship to other modules

Pre-requisite(s): Undergraduate - Before taking this module you must ( pass 1 module from {CH2601, CH2603} and pass at least 1 module from {CH2501, CH2701} ) or ( pass 2 modules from {CH2501, CH2701} and pass CH1601 or pass CH1202 )

Anti-requisite(s): Undergraduate - You cannot take this module if you take CH4456

Learning and teaching methods and delivery

Weekly contact: 2 - 3 lectures per week over 9 - 10 weeks (within Weeks 1-11) and 2 - 3 tutorials in total, plus a half-day site visit.

Scheduled learning hours: 20

Guided independent study hours: 80

Assessment pattern

As used by St Andrews: 2-hour Written Examination = 100%

As defined by QAA
Written examinations : 100%
Practical examinations : 0%
Coursework: 0%

Re-assessment: Oral Re-assessment = 100%

Personnel

Module coordinator: Dr E R Kay
Module teaching staff: Dr E R Kay, Dr A Watson
Module coordinator email ek28@st-andrews.ac.uk