University of St Andrews

Key information

SCOTCAT credits : 15

ECTS credits : 7

Level : SCQF level 10

Semester: 1

Availability restrictions: Not automatically available to General Degree students

Planned timetable: To be arranged.

Highly-efficiently chromosomal DNA replication is essential for all forms of cellular life on Earth and requires the complex interplay of a large range of protein factors in a temporally- and spatially-coordinated manner. In humans, defects in the replication process may lead to genetic disease or cancer. This module will summarise current knowledge of the enzymes and mechanisms of chromosomal DNA replication in bacterial, archaeal and eukaryotic cells with particular emphasis on exploring the diverse range of experimental systems and techniques used in the laboratory to probe the structure, function and regulation of the replication apparatus. Similarities and differences between cellular and viral DNA replication strategies will be explored and diverse aspects of the evolution of the replication machinery highlighted.

Relationship to other modules

Pre-requisite(s): Before taking this module you must pass BL3301 and pass BL3302

Learning and teaching methods and delivery

Weekly contact: 1 x 2-hour seminar (x 10 weeks)

Assessment pattern

As used by St Andrews: 1.5-hour Written Examination = 40%, Coursework = 60%

As defined by QAA
Written examinations : 40%
Practical examinations : 20%
Coursework: 40%

Re-assessment: 1.5-hour Written Examination = 40%, Coursework = 60%

Personnel

Module coordinator: Dr S A MacNeill
Module teaching staff: Dr S A MacNeill
Module coordinator email sam31@st-andrews.ac.uk