BL4216
Structure-based Drug Discovery
2016-2017
15
7
SCQF level 10
1
Academic year(s): 2016-2017
SCOTCAT credits : 15
ECTS credits : 7
Level : SCQF level 10
Semester: 1
Planned timetable:
The process of developing a new drug from conception to the clinic takes on average 15 years and costs over $800M. There are now many examples of drugs developed based on a knowledge of the three dimensional structure of the target, and all major pharmaceutical companies have structural biology as part of their core drug discovery programmes. Many drugs currently used to combat AIDS were developed from a detailed knowledge of key HIV proteins, as were the two drugs used for influenza. Most major pharmaceutical companies are targeting kinases in the search for new cancer therapies, with international efforts focusing on producing structural details of huge numbers of human kinases.This module will examine case studies of drugs that have been developed with the aid of structure-based methods.
Weekly contact:
Scheduled learning hours: 14
Guided independent study hours: 136
As used by St Andrews:
As defined by QAA
Written examinations : 40%
Practical examinations : 40%
Coursework: 20%